MC2R polyclonal antibody
产品名称： MC2R polyclonal antibody
英文名称： MC2R polyclonal antibody
产品编号： PAB7439
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of MC2R.
- Immunogen:
- A synthetic peptide corresponding to human MC2R.
- Sequence:
- ENINNTARNNSDC
- Host:
- Goat
- Theoretical MW (kDa):
- 33.9
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:32000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Human melanocortin receptor 2 expression and functionality: effects of protein kinase A and protein kinase C on desensitization and internalization.
Kilianova Z, Basora N, Kilian P, Payet MD, Gallo-Payet N.Endocrinology. 2006 May;147(5):2325-37. Epub 2006 Feb 23.
- Entrez GeneID:
- 4158
- Protein Accession#:
- NP_000520.1
- Gene Name:
- MC2R
- Gene Alias:
- ACTHR,MGC125798
- Gene Description:
- melanocortin 2 receptor (adrenocorticotropic hormone)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. [provided by RefSeq
- Other Designations:
- ACTH receptor,MC2 receptor,OTTHUMP00000162512,adrenocorticotropic hormone receptor,corticotropin receptor,melanocortin 2 receptor
- Gene Pathway
- Related Disease
- Addison Disease
- Breast Neoplasms
- Chronic Disease
- Depressive Disorder, Major
- Diabetes Mellitus, Type 2
- Epilepsy
- Genetic Diseases, Inborn
- Genetic Predisposition to Disease
- Heroin Dependence
- Mental Disorders
- Musculoskeletal Diseases
- Obesity
- Obesity
- Obesity, Morbid
- Ovarian Failure, Premature
- Pain
- Polycystic Ovary Syndrome
- Prostate cancer
- Prostatic Neoplasms