SIAH2 monoclonal antibody, clone 24E6H3
产品名称: SIAH2 monoclonal antibody, clone 24E6H3
英文名称: SIAH2 monoclonal antibody, clone 24E6H3
产品编号: MAB2298
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against synthetic peptide of SIAH2.
- Immunogen:
- A synthetic peptide corresponding to amino acids 1-100 of drosophila SIAH2.
- Host:
- Mouse
- Reactivity:
- Fruit fly, Human, Pig
- Specificity:
- This antibody is specific to human SIAH2 and Drosophila SINA in proliferating cells and stem cells. This antibody does not detect Drosophila SINAH or normal, nondividing cells.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In tissue culture supernatant (0.1% sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Immunocytochemistry (1:5-1:10)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:40-1:50)
Immunohistochemistry (Frozen sections) (1:40-1:50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Effect of disrupting seven-in-absentia homolog 2 function on lung cancer cell growth.
Ahmed AU, Schmidt RL, Park CH, Reed NR, Hesse SE, Thomas CF, Molina JR, Deschamps C, Yang P, Aubry MC, Tang AH.J Natl Cancer Inst. 2008 Nov 19;100(22):1606-29. Epub 2008 Nov 11.
- 2.
- Inhibition of RAS-mediated transformation and tumorigenesis by targeting the downstream E3 ubiquitin ligase seven in absentia homologue.
Schmidt RL, Park CH, Ahmed AU, Gundelach JH, Reed NR, Cheng S, Knudsen BE, Tang AH.Cancer Res. 2007 Dec 15;67(24):11798-810.
- Applications
- Immunohistochemistry
- Immunohistochemical staining of SIAH2 on human colorectal adenocarcinoma with SIAH2 monoclonal antibody, clone 24E6H3 (Cat # MAB2298). Staining of SIAH was not observed in normal colon epithelium. Photos courtesy of Dr. Amy Tang, Mayo Clinic Cancer Center.