UBE2C polyclonal antibody
产品名称： UBE2C polyclonal antibody
英文名称： UBE2C polyclonal antibody
产品编号： PAB6221
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of UBE2C.
- Immunogen:
- A synthetic peptide corresponding to human UBE2C.
- Sequence:
- C-QETYSKQVTSQEP
- Host:
- Goat
- Theoretical MW (kDa):
- 19.7, 17.4, 16.7, 15
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:32000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase.
Townsley FM, Aristarkhov A, Beck S, Hershko A, Ruderman JV.Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2362-7.
- Application Image
- Western Blot
- ELISA
- Entrez GeneID:
- 11065
- Protein Accession#:
- NP_008950
- Gene Name:
- UBE2C
- Gene Alias:
- UBCH10,dJ447F3.2
- Gene Description:
- ubiquitin-conjugating enzyme E2C
- Omim ID:
- 605574
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000031653,OTTHUMP00000031655,cyclin-selective ubiquitin carrier protein,mitotic-specific ubiquitin-conjugating enzyme,ubiquitin carrier protein E2-C,ubiquitin-protein ligase C
- Gene Pathway
- Related Disease