CDC42 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： CDC42 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： CDC42 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00000998-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human CDC42 protein.
- Immunogen:
- CDC42 (NP_001782.1, 1 a.a. ~ 191 a.a) full-length human protein.
- Sequence:
- MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of CDC42 expression in transfected 293T cell line (H00000998-T02) by CDC42 MaxPab polyclonal antibody.
Lane 1: CDC42 transfected lysate(21.30 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- In situ Proximity Ligation Assay (Cell)
- Proximity Ligation Analysis of protein-protein interactions between CDC42 and MAPK8 HeLa cells were stained with anti-CDC42 rabbit purified polyclonal 1:1200 and anti-MAPK8 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
- Entrez GeneID:
- 998
- GeneBank Accession#:
- NM_001791
- Protein Accession#:
- NP_001782.1
- Gene Name:
- CDC42
- Gene Alias:
- CDC42Hs,G25K
- Gene Description:
- cell division cycle 42 (GTP binding protein, 25kDa)
- Omim ID:
- 116952
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- GTP-binding protein, 25kD,OTTHUMP00000002834,OTTHUMP00000002926,cell division cycle 42,cell division cycle 42 (GTP binding protein, 25kD),cell division cycle 42 (GTP-binding protein, 25kD),dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)),d
- Gene Pathway
- Adherens junction
- Axon guidance
- Chemokine signaling pathway
- Endocytosis
- Epithelial cell signaling in Helicobacter pylori infection
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- GnRH signaling pathway
- Leukocyte transendothelial migration
- MAPK signaling pathway
- Neurotrophin signaling pathway
- Pancreatic cancer
- Pathogenic Escherichia coli infection - EHEC
- Pathways in cancer
- Regulation of actin cytoskeleton
- Renal cell carcinoma
- T cell receptor signaling pathway
- Tight junction
- VEGF signaling pathway